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Nucleophosmin is essential for c-Myc nucleolar localization and c-Myc-mediated rDNA transcription

The transcription factor c-Myc has a critical role in cell proliferation and growth. The control of ribosome biogenesis by c-Myc through the regulation of transcription mediated by all three RNA polymerases is essential for c-Myc-driven proliferation. Specifically, in the nucleolus, c-Myc has been s...

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Hlavní autoři: Li, Zhaoliang, Hann, Stephen R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855075/
https://ncbi.nlm.nih.gov/pubmed/22665062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.227
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