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Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation

The transcription factor c-Myc is essential for cellular proliferation and is one of the most frequently activated oncogenes, but the molecular mechanism mediating its critical role in transformation is unclear. Like c-Myc, multifunctional nucleophosmin (NPM) is tightly regulated during proliferatio...

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Detalhes bibliográficos
Main Authors: Li, Zhaoliang, Boone, David, Hann, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596228/
https://ncbi.nlm.nih.gov/pubmed/19033198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806879105
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