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Influence of Dimethylsulfoxide on RNA Structure and Ligand Binding
Dimethyl sulfoxide (DMSO) is widely used as a cosolvent to solubilize hydrophobic compounds in RNA-ligand binding assays. Although it is known that high concentrations of DMSO (>75%) can significantly affect RNA structure and folding energetics, a thorough analysis of how lower concentrations (&l...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3855037/ https://ncbi.nlm.nih.gov/pubmed/23987474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac402038t |
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