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Amiloride as a new RNA-binding scaffold with activity against HIV-1 TAR
Diversification of RNA-targeted scaffolds offers great promise in the search for selective ligands of therapeutically relevant RNA such as HIV-1 TAR. We herein report the establishment of amiloride as a novel RNA-binding scaffold along with synthetic routes for combinatorial C(5)- and C(6)-diversifi...
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| Pubblicato in: | Medchemcomm |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546750/ https://ncbi.nlm.nih.gov/pubmed/28798862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00729e |
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