Fyn-ADAP signaling via Carma1-Bcl10-MAP3K7 signalosome exclusively regulates inflammatory cytokine production in NK cells

Inflammation is a critical component of the immune response. However, acute or chronic inflammation can be highly destructive. Uncontrolled inflammation forms the basis for allergy, asthma, and multiple autoimmune disorders. Here, we identify a signaling pathway that is exclusively responsible for i...

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Main Authors: Rajasekaran, Kamalakannan, Kumar, Pawan, Schuldt, Kristina M., Peterson, Erik J., Vanhaesebroeck, Bart, Dixit, Vishva, Thakar, Monica S., Malarkannan, Subramaniam
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855032/
https://ncbi.nlm.nih.gov/pubmed/24036998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2708
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