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Phenotypic effects of an induced mutation of the ObRa isoform of the leptin receptor()

Leptin receptors play critical roles in mediating leptin's pleiotropic effects on mammalian physiology. To date, six splice variants of the leptin receptor gene have been identified [1–3]. These splice variants have identical extracellular leptin binding motifs but different intracellular C ter...

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Detalhes bibliográficos
Main Authors: Li, Zhiying, Ceccarini, Giovanni, Eisenstein, Michael, Tan, Keith, Friedman, Jeffrey Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854985/
https://ncbi.nlm.nih.gov/pubmed/24327953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.07.007
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