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Leptin increases striatal dopamine D2 receptor (D2R) binding in leptin-deficient obese (ob/ob) mice
Peripheral and central leptin administration has been shown to mediate central dopamine (DA) signaling. Leptin-receptor deficient rodents show decreased DA D2 receptor (D2R) binding in striatum and unique DA profiles compared to controls. Leptin-deficient mice show increased DA activity in reward-re...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873172/ https://ncbi.nlm.nih.gov/pubmed/20175225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20755 |
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