Bromocriptine Administration Reduces Hyperphagia and Adiposity and Differentially Affects Dopamine D2 Receptor and Transporter Binding in Leptin-Receptor-Deficient Zucker Rats and Rats with Diet-Induced Obesity

BACKGROUND: The dopamine (DA) D(2) receptor (D2R) agonist bromocriptine (BC) decreases body fat in animal and human models and increases lean muscle mass, improves glucose intolerance and insulin resistance, and reduces triglycerides and free fatty acids. We have previously shown a negative correlat...

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Auteurs principaux: Davis, Lisa M., Michaelides, Michael, Cheskin, Lawrence J., Moran, Timothy H., Aja, Susan, Watkins, Paul A., Pei, Zhengtong, Contoreggi, Carlo, McCullough, Karen, Hope, Bruce, Wang, Gene Jack, Volkow, Nora D., Thanos, Panayotis K.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681080/
https://ncbi.nlm.nih.gov/pubmed/18984941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000170586
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