Genes unlinked to the leptin receptor influence urinary albumin excretion in obese Zucker rats

We have previously shown that 90% of outbred obese Zucker Lepr(fa/fa) rats die prematurely of renal disease. Thus, renal disease in obese Zucker Lepr(fa/fa) rats may be caused by the LEPR mutation on chromosome 5, by the obesity, or it may be influenced by Zucker susceptibility alleles of genes on o...

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Autori principali: Kim, Kyoungmi, Warden, Craig H., Griffey, Stephen M., Vilches-Moure, Jose G., Hansen, Susan, Cuppen, Edwin, Nijman, Isaäc J., Chiu, Sally, Stern, Judith S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2010
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869106/
https://ncbi.nlm.nih.gov/pubmed/20159938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.90367.2008
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