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Leptin increases striatal dopamine D2 receptor (D2R) binding in leptin-deficient obese (ob/ob) mice

Peripheral and central leptin administration has been shown to mediate central dopamine (DA) signaling. Leptin-receptor deficient rodents show decreased DA D2 receptor (D2R) binding in striatum and unique DA profiles compared to controls. Leptin-deficient mice show increased DA activity in reward-re...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pfaffly, Jennifer, Michaelides, Michael, Wang, Gene-Jack, Pessin, Jeffrey E., Volkow, Nora D., Thanos, Panayotis K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873172/
https://ncbi.nlm.nih.gov/pubmed/20175225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.20755
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