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Protein-Protein Interactions in a Crowded Environment: An Analysis via Cross-Docking Simulations and Evolutionary Information

Large-scale analyses of protein-protein interactions based on coarse-grain molecular docking simulations and binding site predictions resulting from evolutionary sequence analysis, are possible and realizable on hundreds of proteins with variate structures and interfaces. We demonstrated this on the...

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Autors principals: Lopes, Anne, Sacquin-Mora, Sophie, Dimitrova, Viktoriya, Laine, Elodie, Ponty, Yann, Carbone, Alessandra
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854762/
https://ncbi.nlm.nih.gov/pubmed/24339765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003369
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