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Joint Evolutionary Trees: A Large-Scale Method To Predict Protein Interfaces Based on Sequence Sampling

The Joint Evolutionary Trees (JET) method detects protein interfaces, the core residues involved in the folding process, and residues susceptible to site-directed mutagenesis and relevant to molecular recognition. The approach, based on the Evolutionary Trace (ET) method, introduces a novel way to t...

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Bibliographic Details
Main Authors: Engelen, Stefan, Trojan, Ladislas A., Sacquin-Mora, Sophie, Lavery, Richard, Carbone, Alessandra
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613531/
https://ncbi.nlm.nih.gov/pubmed/19165315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000267
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