The epigenetic modifiers 5-aza-2'-deoxycytidine and trichostatin A influence adipocyte differentiation in human mesenchymal stem cells

Epigenetic mechanisms such as DNA methylation and histone modification are important in stem cell differentiation. Methylation is principally associated with transcriptional repression, and histone acetylation is correlated with an active chromatin state. We determined the effects of these epigeneti...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zych, J., Stimamiglio, M.A., Senegaglia, A.C., Brofman, P.R.S., Dallagiovanna, B., Goldenberg, S., Correa, A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Associação Brasileira de Divulgação Científica 2013
Gaiak:
Biomedical Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854397/
https://ncbi.nlm.nih.gov/pubmed/23797495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20132893
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