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Transcriptional regulation and its misregulation in Alzheimer’s disease

Alzheimer’s disease (AD) is a devastating neurodegenerative disorder characterized by loss of memory and cognitive function. A key neuropathological event in AD is the accumulation of amyloid-β (Aβ) peptide. The production and clearance of Aβ in the brain are regulated by a large group of genes. The...

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Bibliographic Details
Main Authors: Chen, Xiao-Fen, Zhang, Yun-wu, Xu, Huaxi, Bu, Guojun
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854070/
https://ncbi.nlm.nih.gov/pubmed/24144318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-6-44
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