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Investigating intratumour heterogeneity by single-cell sequencing

Intratumour heterogeneity is a longstanding field of focus for both researchers and clinicians. It refers to the diversity amongst cells within the same tumour. Two major hypotheses have attempted to explain the existence of intratumour heterogeneity: (i) the clonal evolution (CE) theory and (ii) th...

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Autors principals: Ren, Shan-Cheng, Qu, Min, Sun, Ying-Hao
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854033/
https://ncbi.nlm.nih.gov/pubmed/24141534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2013.106
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