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Investigating intratumour heterogeneity by single-cell sequencing

Intratumour heterogeneity is a longstanding field of focus for both researchers and clinicians. It refers to the diversity amongst cells within the same tumour. Two major hypotheses have attempted to explain the existence of intratumour heterogeneity: (i) the clonal evolution (CE) theory and (ii) th...

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Detalhes bibliográficos
Main Authors: Ren, Shan-Cheng, Qu, Min, Sun, Ying-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3854033/
https://ncbi.nlm.nih.gov/pubmed/24141534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aja.2013.106
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