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Overexpression of mutant cell division cycle 25 homolog B (CDC25B) enhances the efficiency of selection in Chinese hamster ovary cells

The effects of mutant cell division cycle 25 homolog B (CDC25B) overexpression on the generation of cells producing a monoclonal antibody were investigated in Chinese hamster ovary (CHO) cells. Mutant CDC25B (m-CDC25B) expression plasmids were transfected into CHO DG44-derived cells producing a mono...

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Detalhes bibliográficos
Main Authors: Lee, Kyoung Ho, Tsutsui, Tomomi, Honda, Kohsuke, Ohtake, Hisao, Omasa, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853641/
https://ncbi.nlm.nih.gov/pubmed/24248275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-013-9662-3
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