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Decipher β2-microglobulin: Gain- or loss-of-function (a mini-review)
β2-microglobulin (β2M) functions as a chaperon to maintain structural stability of MHC class I complex that is associated with antigen presentation to cytotoxic (CD8+) T lymphocytes. Cancerous cells in β2M loss-of-function are thought to avoid immune surveillance. As increased level of β2M present i...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
International Scientific Literature, Inc.
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3853100/ https://ncbi.nlm.nih.gov/pubmed/24146000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSMBR.889457 |
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