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Conformational Dynamics of Calcium-Triggered Activation of Fusion by Synaptotagmin
Synaptotagmin triggers rapid exocytosis of neurotransmitters from synaptic vesicles in response to Calcium (Ca(2+)) ions. Here, we use a novel Nanodisc-based system, designed to be a soluble mimetic of the clamped synaptic vesicle-bilayer junction, combined with fluorescence resonance energy transfe...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3853086/ https://ncbi.nlm.nih.gov/pubmed/24314081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.10.029 |
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