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Joint Linkage and Association Analysis with Exome Sequence Data Implicates SLC25A40 in Hypertriglyceridemia

Hypertriglyceridemia (HTG) is a heritable risk factor for cardiovascular disease. Investigating the genetics of HTG may identify new drug targets. There are ∼35 known single-nucleotide variants (SNVs) that explain only ∼10% of variation in triglyceride (TG) level. Because of the genetic heterogeneit...

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書誌詳細
主要な著者: Rosenthal, Elisabeth A., Ranchalis, Jane, Crosslin, David R., Burt, Amber, Brunzell, John D., Motulsky, Arno G., Nickerson, Deborah A., Wijsman, Ellen M., Jarvik, Gail P.
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852929/
https://ncbi.nlm.nih.gov/pubmed/24268658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2013.10.019
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