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Linkage and association analyses identify a candidate region for apoB level on chromosome 4q32.3 in FCHL families

Familial combined hyperlipidemia (FCHL) is a complex trait leading to cardiovascular disease (CVD) risk. Elevated levels and size of apolipoprotein B (apoB) and low-density lipoprotein (LDL) are associated with FCHL, which is genetically heterogeneous and is likely caused by rare variants. We carrie...

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Detalhes bibliográficos
Main Authors: Wijsman, Ellen M., Rothstein, Joseph H., Igo, Robert P., Brunzell, John D., Motulsky, Arno G., Jarvik, Gail P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877194/
https://ncbi.nlm.nih.gov/pubmed/20383777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-010-0819-2
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