Direct DNA and PNA probe binding to telomeric regions without classical in situ hybridization

BACKGROUND: Fluorescence in situ Hybridization (FISH) utilizes peptide nucleic acid (PNA) probes to identify specific DNA sequences. Traditional techniques have required the heat denaturing of the DNA in formamide followed by multiple hours at moderated temperatures to allow the probe to hybridize t...

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Main Authors: Genet, Matthew D, Cartwright, Ian M, Kato, Takamitsu A
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2013
Ábhair:
Methodology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852893/
https://ncbi.nlm.nih.gov/pubmed/24103162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-6-42
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