Direct DNA and PNA probe binding to telomeric regions without classical in situ hybridization

BACKGROUND: Fluorescence in situ Hybridization (FISH) utilizes peptide nucleic acid (PNA) probes to identify specific DNA sequences. Traditional techniques have required the heat denaturing of the DNA in formamide followed by multiple hours at moderated temperatures to allow the probe to hybridize t...

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Dettagli Bibliografici
Autori principali: Genet, Matthew D, Cartwright, Ian M, Kato, Takamitsu A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Methodology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852893/
https://ncbi.nlm.nih.gov/pubmed/24103162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-6-42
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