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Observation and Quantification of Telomere and Repetitive Sequences Using Fluorescence In Situ Hybridization (FISH) with PNA Probes in Caenorhabditis elegans

Telomere is a ribonucleoprotein structure that protects chromosomal ends from aberrant fusion and degradation. Telomere length is maintained by telomerase or an alternative pathway, known as alternative lengthening of telomeres (ALT)(1). Recently, C. elegans has emerged as a multicellular model orga...

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Detalles Bibliográficos
Publicado en:J Vis Exp
Main Authors: Seo, Beomseok, Lee, Junho
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5091719/
https://ncbi.nlm.nih.gov/pubmed/27583462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/54224
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