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Direct DNA and PNA probe binding to telomeric regions without classical in situ hybridization
BACKGROUND: Fluorescence in situ Hybridization (FISH) utilizes peptide nucleic acid (PNA) probes to identify specific DNA sequences. Traditional techniques have required the heat denaturing of the DNA in formamide followed by multiple hours at moderated temperatures to allow the probe to hybridize t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3852893/ https://ncbi.nlm.nih.gov/pubmed/24103162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8166-6-42 |
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