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Empirical assessment of sequencing errors for high throughput pyrosequencing data

BACKGROUND: Sequencing-by-synthesis technologies significantly improve over the Sanger method in terms of speed and cost per base. However, they still usually fail to compete in terms of read length and quality. Current high-throughput implementations of the pyrosequencing technique yield reads whos...

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Hlavní autoři: da Fonseca, Paulo GS, Paiva, Jorge AP, Almeida, Luiz GP, Vasconcelos, Ana TR, Freitas, Ana T
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852801/
https://ncbi.nlm.nih.gov/pubmed/23339526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-6-25
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