Loading...
Treatment of mouse liver slices with cholestatic hepatotoxicants results in down-regulation of Fxr and its target genes
BACKGROUND: Unexpected cholestasis substantially contributes to drug failure in clinical trials. Current models used for safety assessment in drug development do not accurately predict cholestasis in humans. Therefore, it is of relevance to develop new screening models that allow identifying drugs w...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2013
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3852711/ https://ncbi.nlm.nih.gov/pubmed/24112857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-6-39 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|