Unaltered Liver Regeneration in Post-Cholestatic Rats Treated with the FXR Agonist Obeticholic Acid

In a previous study, obeticholic acid (OCA) increased liver growth before partial hepatectomy (PHx) in rats through the bile acid receptor farnesoid X-receptor (FXR). In that model, OCA was administered during obstructive cholestasis. However, patients normally undergo PHx several days after biliary...

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Foilsithe in:Biomolecules
Main Authors: de Haan, Lianne R., Verheij, Joanne, van Golen, Rowan F., Horneffer-van der Sluis, Verena, Lewis, Matthew R., Beuers, Ulrich H. W., van Gulik, Thomas M., Olde Damink, Steven W. M., Schaap, Frank G., Heger, Michal, Olthof, Pim B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7916678/
https://ncbi.nlm.nih.gov/pubmed/33578971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11020260
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