Simple steatosis sensitizes cholestatic rats to liver injury and dysregulates bile salt synthesis and transport

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disorder. It is uncertain if simple steatosis, the initial and prevailing form of NAFLD, sensitizes the liver to cholestasis. Here, we compared the effects of obstructive cholestasis in rats with a normal liver versus rats wit...

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書誌詳細
出版年:Sci Rep
主要な著者: Lionarons, Daniël A., Heger, Michal, van Golen, Rowan F., Alles, Lindy K., van der Mark, Vincent A., Kloek, Jaap J., de Waart, Dirk R., Marsman, Hendrik A., Rusch, Henny, Verheij, Joanne, Beuers, Ulrich, Paulusma, Coen C., van Gulik, Thomas M.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4989137/
https://ncbi.nlm.nih.gov/pubmed/27535001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31829
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