SHARPIN Regulates Uropod Detachment in Migrating Lymphocytes

Sharpin-deficient mice display a multiorgan chronic inflammatory phenotype suggestive of altered leukocyte migration. We therefore studied the role of SHARPIN in lymphocyte adhesion, polarization and migration. We found that SHARPIN localizes to the trailing edges (uropods) of both mouse and human c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pouwels, Jeroen, De Franceschi, Nicola, Rantakari, Pia, Auvinen, Kaisa, Karikoski, Marika, Mattila, Elina, Potter, Christopher, Sundberg, John P., Hogg, Nancy, Gahmberg, Carl G., Salmi, Marko, Ivaska, Johanna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852511/
https://ncbi.nlm.nih.gov/pubmed/24210817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.011
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