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Transcytosis route mediates rapid delivery of intact antibodies to draining lymph nodes
Lymph nodes (LNs) filter lymph to mount effective immune responses. Small soluble lymph-borne molecules from the periphery enter the draining LNs via a reticular conduit system. Intact antibodies and other larger molecules, in contrast, are physically unable to enter the conduits, and they are thoug...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6668680/ https://ncbi.nlm.nih.gov/pubmed/31232704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125740 |
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