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Transcytosis route mediates rapid delivery of intact antibodies to draining lymph nodes

Lymph nodes (LNs) filter lymph to mount effective immune responses. Small soluble lymph-borne molecules from the periphery enter the draining LNs via a reticular conduit system. Intact antibodies and other larger molecules, in contrast, are physically unable to enter the conduits, and they are thoug...

詳細記述

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書誌詳細
出版年:J Clin Invest
主要な著者: Kähäri, Laura, Fair-Mäkelä, Ruth, Auvinen, Kaisa, Rantakari, Pia, Jalkanen, Sirpa, Ivaska, Johanna, Salmi, Marko
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668680/
https://ncbi.nlm.nih.gov/pubmed/31232704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI125740
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