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A novel histone deacetylase inhibitor prevents IL‐1β induced metabolic dysfunction in pancreatic β‐cells

The histone deacetylase (HDAC) inhibitor trichostatin A (TSA) has recently been shown to inhibit deleterious effects of cytokines on β‐cells, but it is unable to protect β‐cells from death due to its own cytotoxicity. Herein, we investigated novel HDAC inhibitors for their cytoprotective effects aga...

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Bibliografski detalji
Glavni autori: Susick, Laura, Senanayake, Thulani, Veluthakal, Rajakrishnan, Woster, Patrick M., Kowluru, Anjaneyulu
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852426/
https://ncbi.nlm.nih.gov/pubmed/20141611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00672.x
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