A novel histone deacetylase inhibitor prevents IL‐1β induced metabolic dysfunction in pancreatic β‐cells

The histone deacetylase (HDAC) inhibitor trichostatin A (TSA) has recently been shown to inhibit deleterious effects of cytokines on β‐cells, but it is unable to protect β‐cells from death due to its own cytotoxicity. Herein, we investigated novel HDAC inhibitors for their cytoprotective effects aga...

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Bibliographic Details
Main Authors: Susick, Laura, Senanayake, Thulani, Veluthakal, Rajakrishnan, Woster, Patrick M., Kowluru, Anjaneyulu
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2009
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852426/
https://ncbi.nlm.nih.gov/pubmed/20141611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2008.00672.x
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