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Essential Role of NADPH Oxidase-Dependent Reactive Oxygen Species Generation in Regulating MicroRNA-21 Expression and Function in Prostate Cancer

Aims: Oncogenic microRNAs (miRs) promote tumor growth and invasiveness. One of these, miR-21, contributes to carcinogenesis in prostate and other cancers. In the present study, we tested the hypothesis that NADPH oxidase-dependent reactive oxygen species (ROS) regulate the expression and function of...

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Detalhes bibliográficos
Main Authors: Jajoo, Sarvesh, Mukherjea, Debashree, Kaur, Tejbeer, Sheehan, Kelly E., Sheth, Sandeep, Borse, Vikrant, Rybak, Leonard P., Ramkumar, Vickram
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852344/
https://ncbi.nlm.nih.gov/pubmed/23682737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4820
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