PKPD Modeling of VEGF, sVEGFR-2, sVEGFR-3, and sKIT as Predictors of Tumor Dynamics and Overall Survival Following Sunitinib Treatment in GIST

The predictive value of longitudinal biomarker data (vascular endothelial growth factor (VEGF), soluble VEGF receptor (sVEGFR)-2, sVEGFR-3, and soluble stem cell factor receptor (sKIT)) for tumor response and survival was assessed based on data from 303 patients with imatinib-resistant gastrointesti...

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Hlavní autoři: Hansson, E K, Amantea, M A, Westwood, P, Milligan, P A, Houk, B E, French, J, Karlsson, M O, Friberg, L E
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852160/
https://ncbi.nlm.nih.gov/pubmed/24257372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2013.61
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