PKPD Modeling of VEGF, sVEGFR-2, sVEGFR-3, and sKIT as Predictors of Tumor Dynamics and Overall Survival Following Sunitinib Treatment in GIST

The predictive value of longitudinal biomarker data (vascular endothelial growth factor (VEGF), soluble VEGF receptor (sVEGFR)-2, sVEGFR-3, and soluble stem cell factor receptor (sKIT)) for tumor response and survival was assessed based on data from 303 patients with imatinib-resistant gastrointesti...

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Bibliografiska uppgifter
Huvudupphovsmän: Hansson, E K, Amantea, M A, Westwood, P, Milligan, P A, Houk, B E, French, J, Karlsson, M O, Friberg, L E
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2013
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852160/
https://ncbi.nlm.nih.gov/pubmed/24257372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2013.61
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