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Asymmetry in Erythroid-Myeloid Differentiation Switch and the Role of Timing in a Binary Cell-Fate Decision

GATA1-PU.1 genetic switch is a paradigmatic genetic switch that governs the differentiation of progenitor cells into two different fates, erythroid and myeloid fates. In terms of dynamical model representation of these fates or lineages corresponds to stable attractor and choosing between the attrac...

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Detalhes bibliográficos
Main Authors: Alagha, Afnan, Zaikin, Alexey
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851994/
https://ncbi.nlm.nih.gov/pubmed/24367366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00426
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