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The erythroid/myeloid lineage fate paradigm takes a new player

This issue of The EMBO Journal features a new paradigm for cell lineage commitment. By studying early haematopoiesis in zebrafish, Roger Patient and colleagues characterize the Tif1 gamma-ligase as a context-specific regulator of Gata1/PU1-driven fate decisions.

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Bibliografiske detaljer
Main Authors: Xu, Jian, Orkin, Stuart H
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3061040/
https://ncbi.nlm.nih.gov/pubmed/21407249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.45
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