Aberrantly methylated genes in human papillary thyroid cancer and their association with BRAF/RAS mutation

Cancer arises through accumulation of epigenetic and genetic alteration. Aberrant promoter methylation is a common epigenetic mechanism of gene silencing in cancer cells. We here performed genome-wide analysis of DNA methylation of promoter regions by Infinium HumanMethylation27 BeadChip, using 14 c...

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Autori principali: Kikuchi, Yasuko, Tsuji, Eiichi, Yagi, Koichi, Matsusaka, Keisuke, Tsuji, Shingo, Kurebayashi, Junichi, Ogawa, Toshihisa, Aburatani, Hiroyuki, Kaneda, Atsushi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2013
Soggetti:
Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851831/
https://ncbi.nlm.nih.gov/pubmed/24367375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2013.00271
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