Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers

A majority of breast cancers are estrogen receptor (ER) positive and have a luminal epithelial phenotype. However, these ER(+) tumors often contain heterogeneous subpopulations of ER(−) tumor cells. We previously identified a population of cytokeratin 5 (CK5) positive cells within ER(+) and progeste...

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Bibliographic Details
Main Authors: Kabos, Peter, Haughian, James M., Wang, Xinshuo, Dye, Wendy W., Finlayson, Christina, Elias, Anthony, Horwitz, Kathryn B., Sartorius, Carol A.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851293/
https://ncbi.nlm.nih.gov/pubmed/20665103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-010-1078-6
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