The proteases HtrA2/Omi and UCH-L1 regulate TNF-induced necroptosis

BACKGROUND: In apoptosis, proteolysis by caspases is the primary mechanism for both initiation and execution of programmed cell death (PCD). In contrast, the impact of proteolysis on the regulation and execution of caspase-independent forms of PCD (programmed necrosis, necroptosis) is only marginall...

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Bibliografiske detaljer
Main Authors: Sosna, Justyna, Voigt, Susann, Mathieu, Sabine, Kabelitz, Dieter, Trad, Ahmad, Janssen, Ottmar, Meyer-Schwesinger, Catherine, Schütze, Stefan, Adam, Dieter
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850939/
https://ncbi.nlm.nih.gov/pubmed/24090154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-76
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