Dysregulation of the complement cascade in the hSOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis

BACKGROUND: Components of the innate immune complement system have been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS); however, a comprehensive examination of complement expression in this disease has not been performed. This study therefore aimed to determine the expression...

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Hlavní autoři: Lee, John D, Kamaruzaman, Nur A, Fung, Jenny NT, Taylor, Stephen M, Turner, Bradley J, Atkin, Julie D, Woodruff, Trent M, Noakes, Peter G
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850877/
https://ncbi.nlm.nih.gov/pubmed/24067070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-119
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