A Mononucleotide Markers Panel to Identify hMLH1/hMSH2 Germline Mutations

Hereditary NonPolyposis Colorectal Cancer (Lynch syndrome) is an autosomal dominant disease caused by germline mutations in a class of genes deputed to maintain genomic integrity during cell replication, mutations result in a generalized genomic instability, particularly evident at microsatellite lo...

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Bibliografiske detaljer
Main Authors: Pedroni, M., Roncari, B., Maffei, S., Losi, L., Scarselli, A., Di Gregorio, C., Marino, M., Roncucci, L., Benatti, P., Ponti, G., Rossi, G., Menigatti, M., Viel, A., Genuardi, M., de Leon, M. Ponz
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2007
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850839/
https://ncbi.nlm.nih.gov/pubmed/17473388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2007/703129
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