17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.

The 4-hydroxy metabolite of 17 beta-estradiol (E2) has been implicated in the carcinogenicity of this hormone. Previous studies showed that aryl hydrocarbon-receptor agonists induced a cytochrome P450 that catalyzed the 4-hydroxylation of E2. This activity was associated with human P450 1B1. To dete...

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Bibliografske podrobnosti
Main Authors: Hayes, C L, Spink, D C, Spink, B C, Cao, J Q, Walker, N J, Sutter, T R
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC38505/
https://ncbi.nlm.nih.gov/pubmed/8790407
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