17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.
The 4-hydroxy metabolite of 17 beta-estradiol (E2) has been implicated in the carcinogenicity of this hormone. Previous studies showed that aryl hydrocarbon-receptor agonists induced a cytochrome P450 that catalyzed the 4-hydroxylation of E2. This activity was associated with human P450 1B1. To dete...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38505/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8790407/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.18.9776 |
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