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Calorie restriction and sirtuins revisited

Calorie or dietary restriction (CR) has attracted attention because it is the oldest and most robust way to extend rodent life span. The idea that the nutrient sensors, termed sirtuins, might mediate effects of CR was proposed 13 years ago and has been challenged in the intervening years. This revie...

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Bibliografiska uppgifter
Huvudupphovsman: Guarente, Leonard
Materialtyp: Artigo
Språk:Inglês
Publicerad: Cold Spring Harbor Laboratory Press 2013
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3850092/
https://ncbi.nlm.nih.gov/pubmed/24115767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.227439.113
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