Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice

Lignende værker

• Suppression of IRAK1 or IRAK4 Catalytic Activity, but Not Type 1 IFN Signaling, Prevents Lupus Nephritis in Mice Expressing a Ubiquitin Binding–Defective Mutant of ABIN1
  af: Nanda, Sambit K., et al.
  Udgivet: (2016)
• Why are the phenotypes of TRAF6 knock-in and TRAF6 knock-out mice so different?
  af: Tsvetana Petrova, et al.
  Udgivet: (2022-01-01)
• Identification of the phosphorylation sites on the E3 ubiquitin ligase Pellino that are critical for activation by IRAK1 and IRAK4
  af: Smith, Hilary, et al.
  Udgivet: (2009)
• The IRAK-catalysed activation of the E3 ligase function of Pellino isoforms induces the Lys(63)-linked polyubiquitination of IRAK1
  af: Ordureau, Alban, et al.
  Udgivet: (2008)
• IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation
  af: Lin, Keng-Mean, et al.
  Udgivet: (2014)