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Mitochondrial iron accumulation with age and functional consequences

During the aging process, an accumulation of non-heme iron disrupts cellular homeostasis and contributes to the mitochondrial dysfunction typical of various neuromuscular degenerative diseases. Few studies have investigated the effects of iron accumulation on mitochondrial integrity and function in...

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Bibliographic Details
Main Authors: Seo, Arnold Y., Xu, Jinze, Servais, Stephane, Hofer, Tim, Marzetti, Emanuele, Wohlgemuth, Stephanie E., Knutson, Mitchell D., Chung, Hae Young, Leeuwenburgh, Christiaan
Format: Artigo
Language:Inglês
Published: 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3849824/
https://ncbi.nlm.nih.gov/pubmed/18843794
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