Bioenergetics and permeability transition pore opening in heart subsarcolemmal and interfibrillar mitochondria: effects of aging and lifelong calorie restriction

Loss of cardiac mitochondrial function with age may cause increased cardiomyocyte death through mitochondria-mediated release of apoptogenic factors. We investigated ventricular subsarcolemmal (SSM) and interfibrillar (IFM) mitochondrial bioenergetics and susceptibility towards Ca(2+)-induced permea...

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Main Authors: Hofer, Tim, Servais, Stephane, Seo, Arnold Young, Marzetti, Emanuele, Hiona, Asimina, Upadhyay, Shashank Jagdish, Wohlgemuth, Stephanie Eva, Leeuwenburgh, Christiaan
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680750/
https://ncbi.nlm.nih.gov/pubmed/19428447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mad.2009.01.004
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