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The role of mitochondrial DNA mutations in aging and sarcopenia: Implications for the mitochondrial vicious cycle theory of aging

Aging is associated with a progressive loss of skeletal muscle mass and strength and the mechanisms mediating these effects likely involve mitochondrial DNA (mtDNA) mutations, mitochondrial dysfunction and the activation of mitochondrial mediated apoptosis. Because the mitochondrial genome is densel...

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Autori principali: Hiona, Asimina, Leeuwenburgh, Christiaan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2225597/
https://ncbi.nlm.nih.gov/pubmed/17997255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2007.10.001
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