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Increased RNA oxidative damage and iron content in skeletal muscle with aging and disuse atrophy
Muscle atrophy with aging or disuse is associated with deregulated iron homeostasis and increased oxidative stress likely inflicting damage to nucleic acids. Therefore, we investigated RNA and DNA oxidation, and iron homeostasis in gastrocnemius muscles. Disuse atrophy was induced in 6- and 32-month...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2601529/ https://ncbi.nlm.nih.gov/pubmed/18395385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2008.02.007 |
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